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G551D Mutation

Showing 1 - 25 of 4,351
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Solid Tumor, Advanced Solid Tumor, NSCLC Trial (MRTX1133)

Not yet recruiting
  • Solid Tumor
  • +4 more
  • (no location specified)
Feb 21, 2023

KRAS P.G12C Trial in Worldwide (D3S-001)

Recruiting
  • KRAS P.G12C
  • Detroit, Michigan
  • +12 more
Jan 16, 2023

NSCLC, Non-small Cell Carcinoma, Histiocytic Tumor Trial (BDTX-4933)

Not yet recruiting
  • Non-small Cell Lung Cancer
  • +32 more
  • (no location specified)
Mar 30, 2023

Kalydeco on Upper Airway and Paranasal Sinus Inflammation

Completed
  • Inflammatory Changes in Epithelial Lining Fluid Sampled Non-invasively by Nasal Lavage in CF Patients With G551D Receiving Kalydeco
  • nasal lavage (routine diagnostic procedure in our centre), assessment of symptoms
  • Jena, Germany
    Jena University Hospital, CF Center
Jul 8, 2021

Slow-Flow Vascular Malformation, Fast-Flow Vascular Malformation, Vascular Malformations Trial in Parkville (Alpelisib,

Not yet recruiting
  • Slow-Flow Vascular Malformation
  • +17 more
  • Parkville, Victoria, Australia
    The Royal Children's Hospital
Aug 7, 2023

Lung Cancer Trial in Houston (AMG 510, Cisplatin, Carboplatin)

Recruiting
  • Lung Cancer
  • AMG 510
  • +3 more
  • Houston, Texas
    M D Anderson Cancer Center
Oct 10, 2022

NSCLC, EGFR G719X, EGFR L861Q Trial in Chongqing (Furmonertinib 160 mg, Q.D.)

Recruiting
  • Non-small Cell Lung Cancer
  • +3 more
  • Furmonertinib 160 mg, Q.D.
  • Chongqing, Chongqing, China
  • +2 more
Sep 16, 2022

Solid Tumors, KRAS Mutation Trial in Worldwide (BI 1823911, BI 1701963, Midazolam)

Recruiting
  • Solid Tumors, KRAS Mutation
  • BI 1823911
  • +2 more
  • New York, New York
  • +8 more
Aug 10, 2022

Expanded to Additional Genotypes and Extended for Long Therm

Completed
  • Cystic Fibrosis
    • Birmingham, Alabama
    • +35 more
    Jun 28, 2021

    Cystic Fibrosis Trial in San Francisco (ivacaftor, Placebo)

    Completed
    Has Results
    • Cystic Fibrosis
    • San Francisco, California
      University of California, San Francisco
    Sep 8, 2020

    Locally Advanced Solid Tumor, Metastatic Solid Tumor Trial in United States (NVL-655)

    Recruiting
    • Locally Advanced Solid Tumor
    • Metastatic Solid Tumor
    • Orange, California
    • +13 more
    Jan 31, 2023

    Solid Tumor Trial in United States (ASP3082)

    Recruiting
    • Solid Tumor
    • Santa Monica, California
    • +10 more
    Jan 6, 2023

    Cystic Fibrosis Trial in Worldwide (VX-121/TEZ/D-IVA, ELX/TEZ/IVA, IVA)

    Active, not recruiting
    • Cystic Fibrosis
    • Birmingham, Alabama
    • +169 more
    Dec 22, 2022

    First Line Treatment for BRAFV600E Mutant Metastatic Colorectal

    Completed
    • BRAF V600E Mutation Positive
    • Metastatic Colorectal Cancer
    • Non Interventional study
    • St. Veit/Glan, Austria
    • +33 more
    Jan 20, 2023

    NSCLC With Mutation in Epidermal Growth Factor Receptor Trial in Kunming (Combined therapy of anlotinib and aumolertinib)

    Recruiting
    • Non-Small Cell Lung Cancer With Mutation in Epidermal Growth Factor Receptor
    • Combined therapy of anlotinib and aumolertinib
    • Kunming, Yunnan, China
      First Affiliated Hospital of Kunming University
    Oct 22, 2023

    Cystic Fibrosis Trial in Worldwide (ELX/TEZ/IVA, IVA, Placebo (matched to ELX/TEZ/IVA))

    Recruiting
    • Cystic Fibrosis
    • Innsbruck, Austria
    • +89 more
    Dec 20, 2022

    NSCLC, Colorectal Cancer, Advanced Solid Tumors Trial in Worldwide (GDC-6036, Atezolizumab, Cetuximab)

    Recruiting
    • Non-Small Cell Lung Cancer
    • +2 more
    • Duarte, California
    • +68 more
    Jan 10, 2023

    CFTR-modulating Triple Therapy Elexacaftor - Tezacaftor -

    Recruiting
    • Cystic Fibrosis
    • Elexacaftor / Ivacaftor / Tezacaftor
    • Erlangen, Bavaria, Germany
      University Hospital Erlange, Department of Pediatrics
    Oct 7, 2022

    NSCLC Trial in Worldwide (Sotorasib)

    Active, not recruiting
    • Non-small Cell Lung Cancer
    • Birmingham, Alabama
    • +65 more
    Nov 29, 2022

    Ivacaftor Treatment in 4 Month to 2 Year Old CF Subjects

    Completed
    • Cystic Fibrosis
    • Philadelphia, Pennsylvania
      Children's Hospital of Philadelphia
    Mar 10, 2022

    Cystic Fibrosis, Mucociliary Clearance Defect Trial in Iowa City, Columbia (Symptom driven performance of airway clearance,

    Not yet recruiting
    • Cystic Fibrosis
    • Mucociliary Clearance Defect
    • Symptom driven performance of airway clearance
    • Continuous daily performance of airway clearance
    • Columbia, Missouri
      University of Missouri Hospital and Clinics
    Dec 12, 2022

    Advanced Solid Tumors, Kirsten Rat Sarcoma (KRAS) pG12C Mutation Trial in Worldwide (Sotorasib, AMG 404, trametinib)

    Recruiting
    • Advanced Solid Tumors
    • Kirsten Rat Sarcoma (KRAS) pG12C Mutation
    • Tucson, Arizona
    • +83 more
    Dec 28, 2022

    Cystic Fibrosis Trial in Worldwide (ELX/TEZ/IVA, IVA)

    Completed
    • Cystic Fibrosis
    • Tucson, Arizona
    • +83 more
    Jan 20, 2023

    NSCLC Trial in Worldwide (Poziotinib)

    Active, not recruiting
    • NSCLC
    • Phoenix, Arizona
    • +62 more
    Jan 27, 2023

    Ovarian Cancer Trial in Worldwide (VS-6766, VS-6766 and Defactinib)

    Recruiting
    • Low Grade Ovarian Serous Adenocarcinoma
    • Ovarian Cancer
    • avutometinib (VS-6766)
    • avutometinib (VS-6766) and Defactinib
    • Scottsdale, Arizona
    • +46 more
    Dec 29, 2022